We use light to control how living cells produce therapeutic proteins — optogenetic cell engineering, custom illumination hardware, and real-time ML bioprocess control — to drive down cost and scale up production of next-generation therapies.
With our technology scaling from the lab to the real world of biomanufacturing, we're now hiring a foundational software engineer to build the platform tying together our hardware, firmware, cloud, and internal tooling — high ownership over architecture and direction. This is a systems role across the hardware/software boundary (not web/SaaS), working directly with embedded, mechanical, data, and even bioprocess engineers.
Looking for: strong systems thinking; Python + one of TS/Go/Rust; cloud-connected services; comfort interfacing and debugging software against hardware (serial, TCP/IP); Linux. MS + 5 yrs or BS + 7 yrs. Bonus: Industrial IoT (MQTT Sparkplug B, OPC UA, SCADA/MES), regulated-industry data integrity (21 CFR Part 11, GAMP 5), or embedded C/C++.
Apply: https://jobs.lever.co/prolific-machines/6d71f9d0-7248-4449-8...
Happy to answer questions: matt dot fay at prolific dash machines dot com.
Wand (40M+ gamers) builds the augmentation and intelligence layer for PC gaming — real-time game-state reading powering a unified ecosystem across desktop, web, and native in-game overlays. Contextual help, interactive maps, and video clipping delivered exactly when a player needs it, without alt-tabbing out of the game.
We're hiring a senior IC to own meaningful parts of the native infrastructure underneath all of that. This is platform-team work at the seam between Windows, third-party game engines, and our product. You'll make architecture calls the rest of engineering lives with for years, and you'll measure success by what other teams shipped on top of your foundation — not by what you personally wrote. Recently shipped: a plugin system for safe in-process extensions; current work includes a Lua scripting layer on top of it.
What we're looking for: - 7+ years C++, meaningful time on tools/engines/platform systems where your users were other engineers - Deep Windows native: Win32/64, DLL lifecycles, hooking, IPC, process/thread management, WinDbg/Process Monitor - Strong concurrent programming — you spot races and ordering bugs in review without a checklist - Plugin/extensibility experience: you've designed an interface someone else built on, and lived with the result - Outcome-oriented, low-ego
Bonus: Unreal/Unity internals, full-stack TS/Electron down to C++, scripting/SDK layer (Lua/AngelScript/DSL), OBS or video capture internals, gRPC/Protobuf/FlatBuffers.
Fully remote, competitive comp + equity.
Elucid builds FDA-cleared AI software that analyzes cardiac CT scans to characterize plaque and predict heart attack and stroke risk. The world's best cardiologists use our output to make treatment decisions for real patients. As such, our platform is regulated as a Software as a Medical Device (SaMD) product by the FDA and we operate under HIPAA, ISO 13485, and ISO 27001.
We're hiring a Principal Platform Engineer to own our cloud infrastructure and developer platform: AWS, containers, Terraform, CI/CD, observability, and the self-service tooling that lets our application teams ship quickly inside a regulated SDLC.
We are looking for: 7+ years in DevOps/SRE/platform roles, deep AWS, strong IaC, comfort with containers (ECS/Fargate, Kubernetes), and one language you reach for when building tooling (Python, Go, Rust, Ruby, C++). Healthcare or regulated-industry experience is a plus, but not a requirement.
On-call is a shared rotation, roughly 2–3 weeks per quarter, business-day coverage only (9am–midnight ET, no overnights).
Apply at the link above.
ClickHouse is a popular, Open-Source OLAP Database. We are ClickHouse Inc, the company behind the database aiming to build the best in class real time data warehouse.
What we are looking for:
Distributed Systems / Cloud Engineers to build
- AutoScaling Systems for a Cloud Database - A Distributed Caching Layer on top of S3 [0] If you have experience in productionizing and maintaining distributed systems cloud-based multi-tenant caches - you would fit right in.We also maintain our own ClickHouse based Data Infrastructure. Bonus points if you've worked on auto-scaling or other data-driven forecasting challenges in the past.
Can work in a fast moving scale-up environment. Proactive and hands on. You must be independent and self-organized. Database SRE / Cache Operations experience Go, Kubernetes, Distributed Systems in general You will need to be able to do On-Call - debugging production infra, db or cache issues Low-level database programming (C++, ClickHouse) - This is crucial for the cache. If you want to work on operating production critical databases/caches in the cloud on or write data-driven algorithms for autoscaling, consider applying! Send me an email: manish.gill [at] clickhouse [dot] com[0] https://clickhouse.com/blog/building-a-distributed-cache-for...
Stpkr Technologies is hiring for the following roles to build the next generation of wearable devices.
We are currently looking for the following 4 roles but we are also open to interviewing any candidates who feel like they will do their best work here - even if your skillset/experience doesn't fit the current defined roles. Our current team doesn't fit the conventional mold, and we don't expect our future hires will either. If you don't fit the advertised roles, just send us a mail per the same process with whatever job title would fit you the best.
Work is in person near Noida Sector 18, walking distance from Sector 18 Metro Station. We prefer in office work, but we are super flexible overall, it will be hands down one of the best work environments you can get. Pay is competitive, and there are opportunities to earn meaningful equity down the line. We prefer current and recent undergraduates for our roles. If you are still in college we welcome you to apply nonetheless provided you can work as an intern for us in person. Super-flexible overall and all of our current team started out as interns.
Hiring across OS, full-stack, and hardware. AI policy across all roles: you should be able to do the work without AI, and much faster with it.
Android Systems Engineer (AOSP/BSP) - Everything at the OS layer. You've rooted phones, flashed custom ROMs, broken and fixed Linux for fun. Comfortable in C/C++. GitHub with kernel-adjacent or LineageOS-type projects a plus. Stack: Android, Linux, C, C++, Java. _Filter: send us something you built where you had to fight the OS or hardware.
Full-Stack Engineer (Apps + Backend + ML) - Everything at the platform layer. Generalist who ships end-to-end. Skill check: can build a crude-but-working facial recognition system (camera → model → DB → backend). (using existing facial recog models) Bonus for weird/constrained hardware work or running ML on edge devices. Stack: Android, Java, Python, TypeScript. _Filter: send the most useful thing you've built and used (no CRUD slop). Even better if you still use it for yourself.
Hardware Engineer - Bring-up/Debug/Integration - Take EVT/DVT boards and make them work. Comfortable with J-Link and IDE debugging, reading schematics and reference designs. KiCad/Altium/EasyEDA hobby work would make you ideal. PetaLinux experience or hunger to learn it. ECE undergrad fine. _Filter: photo of a board you designed or debugged, plus what went wrong.
Hardware Engineer - Power/RF/Wireless - Make the power and RF paths behave on EVT/DVT boards. Hands-on with schematic capture, layout, soldering, scope/logic analyzer. Given two unknowns, you pick one and start measuring. _Filter: sensor fusion work, how noise behaves across protocols, and SPI debug chops.
Founder's Office - Work closely with the founder and the rest of the team to manage the day to day and long term affairs of the company, the Man Friday of the company. Must have a decent degree of technical knowledge (we are a tech company after all) and be efficient at administrative tasks as well as management. Speed and learning ability are prized here, there will not always be a clear path to the work you have to do here, so you will have to figure some of it out on your own.
To apply, contact arnav@stpkr.in with the subject line "HN - Human" and a brief intro for further communication. Attach any documents you deem useful there. Please include the role you are applying for at the top of the email if it is one of the above mentioned, otherwise whatever role fits you best. Shortlisting will be online, interviews will be in person. We are hiring quickly, expect to hear back from us within 2-3 days of applying. If you don't, assume you will not. Thanks for your time!
We are hiring software engineers who enjoy solving important real-world problems and working close to hardware; who learn new domains quickly and prefer practical solutions over over-engineered systems or unnecessary complexity. You’ll work on the projects best suited for you. Projects range widely, and include:
Scientific tools
Automation & robotics (Linux & ROS level)
Embedded C/C++ (typically owned by dedicated firmware engineers, but software engineers are welcome to learn!)
Linux, CUDA, Server engineering for our AI safety, security, and verification work
Custom simulation software (usually python)
Data analysis pipelines (python)
Organisational tooling (Typescript, react, postgres, etc.)
Structure: Small teams of software, mechanical, electronics, and firmware engineers build end-to-end systems, typically shipping within a few months.
Beacon AI builds intelligent systems that make aviation safer and more autonomous. We’ve completed multiple DoD programs and are expanding our team with exceptional technical leaders to push the boundaries of human-machine collaboration in the cockpit. At Beacon, you will lead by example, mentoring and growing a small team of talented engineers (typically 1–2 to start) while staying hands-on in design and execution. You’ll help shape critical systems that advance aviation safety and autonomy, working alongside a team that values effort, creativity, and accountability.
We’re hiring Lead Engineers with 5-9 YOE who love solving complex problems. At Beacon, you’ll own your work end-to-end, from prototype to deployment, and literally see your code take flight in real world aviation environments! Roles:
++ iOS Engineer [Tech Stack: Swift, SwiftUI, UIKit, Mapbox]
++ Senior Security Engineer [SIEM, IDS/IPS, vulnerability scanning, encryption]
++ Infra/Backend Engineer [Tech Stack: AWS]
++ WebApp/FrontEnd Engineer [Tech Stack: Python, Typescript, React]
++ Lead Autonomy/Robotics Engineer [Tech Stack: C++, Python, iOT]
Join us at beaconai.co/careers. Mention in the application that you saw our post on HN.
Company: We're a small scientific software development company that develops custom scientific and engineering analysis applications in domains including: space situational awareness (monitoring the locations, health and status of on-orbit satellites), image simulation, high power microwave systems, modeling and simulation, laser systems modeling, AI/ML including physics-informed neural networks (PINN), human body thermoregulation, computer vision and image processing, high performance computing (HPC), computer aided design (CAD), and more. All exciting applications and no CRUD. We emphasize high quality code and lightweight processes that free software engineers to be productive.
Experience: Except for interns, we currently require a Bachelors degree in physics, engineering, math, computer science, or a related field. Masters or PhD is a plus. (Roughly 25% of our staff have PhDs.)
Technologies: Lots of C++23, Qt 6.9, CMake, git, OpenGL, CUDA, Boost, Jenkins. Windows and Linux, msvc/gcc/clang/clangcl. AI/ML and analysis projects use Python and C++. Web projects use Java and Typescript/React. We're a bit behind the curve on developer AI adoption, and we're okay with that.
Apply online: at https://www.stellarscience.com/careers/.
We melted GPUs chasing Causal AI — now we run one of the world's fastest private supercomputers, the only non-Fortune 500 company on earth operating one. Patented causal math, proving what actually drives revenue for the world's best enterprises.
Hiring: SREs to run our supercomputer, C++ engineers for AI systems, data engineers for enterprise-scale pipelines, and backend Python engineers for the platform.
Customers: NVIDIA, Delta, Mars. $145M Series B. Hiring SREs, C++ AI, data, and backend Python engineers.
We are looking for experienced Site Reliability Engineers and Infrastructure Software Engineers to help build, scale, and secure the foundation of MongoDB Atlas, our globally distributed, multi-cloud database platform running across AWS, GCP, and Azure.
SRE at MongoDB is a builder role. We are heavily focused on making the platform more scalable, resilient, secure and self-service.
We have open roles (Senior, Staff, Lead) across several of our core Infrastructure teams:
- Infrastructure Security (InfraSec): Building infrastructure security controls and security observability tooling leveraging eBPF and Linux security mechanisms.
- Fabric: Building out service mesh, networking, and internal traffic routing.
- Storage Layer Services: Building our next-generation disaggregated storage architectures.
- Fleet Management & Deployments: Automating the lifecycle, deployments, and control planes of massive multi-cloud Kubernetes clusters.
- Atlas Infrastructure: Building core infrastructure operations on hundreds of thousands of Linux servers.
You could be a fit if:
- 5+ years of experience in SWE, SRE, or similar roles.
- Proficiency in at least one programming language: Golang, Rust, Python, C/C++ etc.
- Deep understanding of Linux internals, networking, distributed systems, and/or Kubernetes.
- Familiarity with at least one major cloud provider (AWS, GCP, or Azure).
- A builder's mentality: you think about failure modes, observability, and operability alongside correctness.
For any questions, or to apply directly (please mention HN) email: hani.benhabiles+hn@mongodb.com
When you look at the headers of major websites, you’ll see us. If it has to be performant, secure, scaled worldwide, and always-on, it uses Fastly.
We're a globally edge cloud platform for performance and security, emphasizing open standards, sustainable engineering, and resilience-by-design.
We're hiring across compute, security, platform engineering, network and edge protocols, release engineering, network architecture, client services engineering, and more.
Rather than building walled gardens, we co-founded the Bytecode Alliance, heavily upstream our work to open standards, actively author IETF drafts, and power the global infrastructure for open-source Python, Rust, Ruby, OpenStreetMap, and much more.
The Stack: Rust, C/C++, Go, Javascript, Typescript, WebAssembly (Wasm/WASI), Wasmtime, Cranelift, eBPF/XDP, QUIC, HTTP, TLS, TCP, Varnish/VCL, Linux kernel internals, distributed systems, professional services.
Atom Computing is building large-scale quantum computers using arrays of optically trapped neutral atoms. Learn more at https://atom-computing.com/news-resources/
Our software team works on distributed systems, cloud infrastructure, APIs, developer tooling, orchestration, observability, automation, and high-performance computing that power both research and commercial quantum systems. Quantum computing experience is not required.
Open roles:
- Senior Infrastructure Engineer — Cloud and on-prem infrastructure, developer platforms, observability, automation, and production reliability.
- Senior Software Engineer — Build the software stack behind our quantum computers, including APIs, orchestration, automation, data systems, and developer tooling.
- Software Engineering Manager — Lead a team building the software platform for Atom's quantum systems, spanning APIs, cloud services, researcher workflows, and system architecture.
- Principal Software Engineer — Architect backend services for quantum job orchestration, distributed systems, cloud infrastructure, and production-grade APIs.
STACK: Python, Rust, C++, Terraform, Azure, distributed systems, hybrid cloud infrastructure, and HPC.
Apply: https://jobs.lever.co/atomcomputing - Please mention HN in your application.